Systematic Review of the Effectiveness of Continuous Glucose Monitoring (CGM) on Glucose Control in Type 2 Diabetes

generally accepted target. The goal of diabetes management is to prevent diabetic complications can improve glycemic control and decreases the risk of long-term microvascular complications in diabetes, high rate of hypoglycemia becomes a risk in intensive diabetic management. The fear of hypoglycemia often leads patients to forget the fatal consequences of long-term complications to avert hypoglycemic events with loss of control and cognitive dysfunction. Self-monitoring of blood glucose (SMBG) is a fundamental part of diabetes management. However, SMBG fails to detect nocturnal hypoglycemia and asymptomatic hypoglycemia. Hence, monitoring blood glucose system on a ‘continuous basis’ have been developed. This systematic review aims to support evidence regarding the effects of continuous glucose monitoring system (CGMS) on glycemic control in type 2 diabetes by collecting randomized controlled trials from MEDLINE (pubmed), Scopus, CINAHL, Web of Science and The Cochrane Controlled Trials Register studies presented the positive results in favor of CGMS group (HbA1c decrease; 0.6-1.16% over SMBG use in type 2 diabetes. Keyword: Systematic review, Continuous glucose monitoring (CGM), Type 2 diabetes, T2DM INTRODUCTION Diabetes mellitus is a chronic illness that requires continuing medical care and ongoing patient self-management education including the support to prevent or reduce acute and long-term complications1-4. People who have diabetes mellitus face daily challenges in managing glycemic levels, as well as avoiding hypoglycemic and hyperglycemic excursions. Both severe hypoglycemia and extreme hyperglycemia have an immediate impact on mental and physical functioning. The maintenance of glycemic control within near-normal limits can avoid such a situation the development of secondary microand macrovascular complications. Self monitoring of blood glucose (SMBG), a kind of capillary blood glucose measurement using portable device, has been used to assess blood glucose level . Because of many factors, such as pain and inconvenience, many diabetes feel for SMBG6. In addition, SMBG gives a single instant reading without any information on *Corresponding author: Road, Payathai, Ratchathewi, Bangkok 10400, Thailand  